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pellet insertion site in Maine!

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hormone therapy for men

Studies have shown, men begin losing testosterone at a rate of 3% to 10% per year beginning at age 30. Current medical research now defines a male equivalent to menopause as andropause. Because the testosterone used is totally natural, it is ideal for men who want the benefits of a bio-identical hormone without the drawbacks of a synthetic. Hormonal needs for men have received national attention, but with marginal treatment options available. Hormonal treatments for men can be expensive, require daily consumption, and, in many cases, need to be carefully timed with their partner’s needs for normal sexual activities and pleasure. Bio-identical hormone pellet therapy is the only delivery method of testosterone therapy that gives sustained and consistent testosterone levels throughout the day for four to six months without any “roller coaster” blood levels of testosterone, which can result in mood and energy fluctuations for the patient. BioTE® Medical has had excellent results treating men with bio-identical hormone therapy.


testosterone pellet therapy

  • Testosterone is made in the ovaries and testes

  • Men ages 30-70 lose 1-3% of total testosterone per year

  • Low testosterone results in: Increased risk for Alzheimer’s Disease, increased risk for caridovascular disease, increased risk for prostate cancer and increased risk for sarcopenia

  • Benefits of testosterone include: Enhanced libido, cardiovascular/heart protection, increased energy, enhanced sleep, feeling of overall well-being, improved erections, increased lean body weight (muscle mass), stronger bones & muscles, improved moods, reduced brain fog, improved cognition and prostate protection



There are many benefits to bio-identical hormone replacement therapy (BHRT) for men. Learn how to find out if your male hormones are balanced and what therapies BioTE® Medical may be able to offer you to help you live your best life. BHRT is an acronym which stands for bio-identical hormone replacement therapy. BHRT can help men feel like themselves again. It can also help men who have always suffered from unbalanced hormones feel like themselves for the first time. BHRT may also be able to lower the severity/risk of ailments not directly associated with the reproductive symptoms most directly linked to imbalanced male hormones.


What are bio-identical hormones?

  • The hormones within BHRT pellets are bio-identical, meaning that they are structurally the same as naturally occurring human hormones

  • These hormones are found in nature and are plant derived. This implies that the hormones used in BHRT pellet therapy for men are more natural and may have fewer negative interactions within the body

  • Dosing is tailored to the individual patient

  • Absorbed based on cardiac output, which mimics the body’s production of hormones

  • Less roller coaster effect, resulting in less mood swings

What are BHRT pellets?

  • Pellets contain bio-identical hormones custom compounded in a pharmacy within the United States

  • The quality of the hormones used for BioTE Medical pellets is extremely high and consistently tested in every batch

  • Must comply with CGMP (Current Good Manufacturing Practice) requirements

  • Are inspected by FDA according to a risk-based schedule



  • Dementia takes 15-20 years to develop and begins with Mild Cognitive Impairment

  • MCI begins in the 30s-40s

  • By 80-85, 50% of Americans have dementia

  • Dementia may be accelerate by hormonal and neurotransmitter imbalances

  • Bioidentical hormones increase cerebral blood flow, decrease inflammation, decrease the unhealthy proteins seen in Alcheimer’s, estradoil has better effects on verbal memory and testosterone improves cognition & memory

  • Pellets have 8.3% increase per year in bone density

  • Approximately 4% of muscle mass is lost during the first 3 years of menopause

  • Testosterone increases lean body mass & decreases fat mass

  • Leading cause of morbidity and mortality in the United States

  • Affects 12 million people with 1 million deaths per year

  • Erectile dysfunction predictive of later CVD incident

  • Pellets increase blood flow, decrease inflammation, improve insulin resistance, reduce body fat, and improves HDL (with no adverse effect on platelets)


why does delivery matter?


Learn More About Bioidentical Hormone Therapy Here:


Q. Are pellets FDA approved?

A. The estradiol and testosterone in the BioTE pellet are FDA approved, but the actual pellet is not.

Q. What should I do before the procedure?

A. One week before the procedure, if possible, stop all NSAIDs (aspirin, ibuprofen, acetaminophen, naproxen sodium, etc.). No fasting in advance of the procedure is required.

Q. What test is required before the insertion?

A. BioTE requires, at the minimum, our comprehensive blood panel which can be discussed with your BioTE provider.

Q. Do patients need to stop taking any medications before getting labs drawn?

A. For injectable hormones, BioTE recommends drawing blood the day they are supposed to receive their next shot before they receive their hormones. Men should discontinue their existing hormone therapies 7 days AFTER pelleting. This is often the best method to transition patients from existing hormone therapies.

Q. How big are the pellets and can you feel them?

A. They are about the size of a large grain of rice. Occasionally pellets may be felt underneath the skin. Sometimes the area is more palpable due to swelling. Limit gluteal exercises after insertion can reduce this swelling.

Q. What happens during the in-office insertion?

A. During the in-office visit, which only takes a few minutes, patients are brought into the exam room, and the insertion site is numbed. The most common site of insertion is the upper buttocks. A small incision is then made for the pellet to be inserted. Once the pellet is inserted, the insertion site is covered with a small bandage. You will return 4 weeks after the initial insertion for a follow up blood panel to determine any dosing changes.

Q. Do I need to take supplements in addition to my BioTE pellets?

A. YES. Nutraceutical supplements will be recommended to you by Dr. Holland at your consultation and can be purchased in our office. Supplements are key in providing integrated wellness in the areas of healthy hormone balance, disease prevention and supplementing diets.

Q. What happens during the week following the insertion?

A. After pellet insertion, it’s best to eliminate lower body exercise. This doesn’t include walking, but, extraneous exercise is not recommended. Swimming, hot tubs, and bath tubs are to be avoided, this doesn’t include showers. After removal of the bandage, normal activities may resume.

Q. How often is pellet insertion necessary?

A. Each patient’s symptoms are unique and each patient’s paths to optimization is unique. Your journey will be specialized to fit your specific needs. Just as it doesn’t take you 1-2 weeks to get out of balance, it doesn't resolve that quickly either.

Q. What happens to pellets after insertion?

A. Since the pellets are bio-identical and contain nothing other than the hormone your body naturally produces, the pellets are completely dissolved and absorbed, leaving nothing behind.

Q. How often do you need pellets?

A. For men every 4-6 months. The more patients move, the better they will absorb the pellets, but the faster they will absorb them as well.

Q. Are there side effects to pellet therapy?

A. Less than 2% of patients experience actual side effects. Side effects or secondary responses are minimal and very easily managed. Some reported responses are noticeable in the first two rounds during the initial balancing phase. These include: Mild fluid retention, acne or more growth could occur. You may experience some minimal testicular shrinkage due to the pellets taking over for their natural production.

Q. How long will it take for body changes to occur?

A. An exercise regime & healthy diet is essential in optimizing hormones. Body changes are typically seen with the 2nd and 3rd insertions, typically 4-6 months after initiating therapy.

Q. Can prostate cancer survivors receive pellets?

A. Yes. After the prostate cancer has been treated or removed and the PSA blood test is undetectable, the patient can be pelleted. Testosterone does not cause prostate cancer and has several important effects in the aging male body.